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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c814b6d0d4f3ca1510da6f250007ac4dc72ce622d04c05063ef853e25e73d12' 
  AND token = 'vs8aebjhvF4fuSrw8i9T42COpDSSeNk7lEMutzpcEs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}