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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ce396d581f212ea792ba859d555172bc3c7b647350a59373fa414d422b718d' 
  AND token = 'NV9pLB6v0m4gjb52PZX4slsyq/Klsd6dvI7DIlezX7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}