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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd332be320750db5368d40f4f96613969f2c5ef536cc9769eb9d460a60bf80c00' 
  AND token = 'iQfyLEv3T9MDIKOORzqN1YXNEugYAYXcETL+q0uu3mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}