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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a169118f89cc7728c8d06f2ae81db9043e52a2c627fc7fa7468e94a422add14' 
  AND token = 'rqd2x+J5IodttQaBy6D8o/fp+Qz0c9IzJ+3GDe9boWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}