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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cd21a5fe6d3b65860e2b429669b5086bdf1dd58fe0771743c7d989383c9984' 
  AND token = '50UxbASS6NwFG4Vt/ewNaFUmsPalYzeWvQGaXxB8c6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}