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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701666156adc8d28b1e9a358cc5c2864d626490078ed3ec8877b5227183122f6' 
  AND token = '+2rgCS3T3fFqsyRsnpwxl+RW6xRoYQEhuIdKjNnrrm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}