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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d091e859975cf46989a178dbe251a184304dafac478f6d7c4f797db9a4c3069' 
  AND token = 'Mlmjv64jw5CKByT4OYMl2blP4GCwVXI4rMZMeXv2hM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}