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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ea6f17c0afddcc5061d46f9c963fedd10955907f03773ef12c53a21fccc8214' 
  AND token = 'qEmeygxgDH/My8gRM2XEAPCB4hkdW1MO12UH2gyqjU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}