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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '611ffb587c84d95ab46a61eb353c006068c2c0eb431a9005a8d7a3da14e91455' 
  AND token = 'jKmvSZ0/aKYOP/x4JlaGiwcVbZcxB9Jqw01srVQ4yKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}