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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f94a24e6c430152b18c32519e9dd880d2721dd7d17f5c718d48933d2d2c69892' 
  AND token = 'Q2DBpcMgwFsaTy8PRo2+rYflIGih5/sPTpBr+cjRt2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}