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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a1102cd8a779a552cb449f495bae28991898fba67f5c1cc0fc822372195ce0' 
  AND token = 'XAGkQyZ3twUuu9ppfQetbwuDcf02C+1LU4X1HWiccVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}