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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72241ff4bcf48789446981fd4ae1667982fc5e4a8fca4fd6b39a3e703cdab8ea' 
  AND token = 'sQ3v50lnr3oKAGPRmYrCetWwjoVtCSGTX396tBBdQVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}