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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afcc7a50ee773ff22945d14869d666275526e539389b388cc085e9454035b5c5' 
  AND token = 'I7FJ589+UL6ttEi+Cvvc+nHHy26ry9UasIkmM4vNgWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}