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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45da1a7c1abf9a0ad93823a5c01f6f211d462249164c8a7f1387a6d0e00722e' 
  AND token = '2zJqjiewBKG/7NFiThTiQvawSActpmkK5eZfIABqpx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}