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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba1e3fd0e44a206e563e4a587b1f0231129565ea11b22b2c95f44a40b5e4599' 
  AND token = 'EwTv73Vhhf1ZRkwEs1gN4kovU1oiNckXWCin6AIuPSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}