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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f3762c4f8ecb5065de37f59e4e81864744d3ad72c778af4a37042dcb8ac919' 
  AND token = 's0JVgrtDaEYPWjfrk8ZQ+i8rVrddrBXzkFhZg7V7FpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}