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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5ab8691a3503d632999cf82049b099d7a2fa69f67c67822b6f26dc9ac1e575' 
  AND token = 'ce/i9A5TkG+vY/rbkjOPoNnzx3oWoULHkK4MNs3Vmjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}