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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750e1f8cf901454058bec7dfb80889ca50cb65c91ba0e07c9d6cfc686205e4e2' 
  AND token = '1bpYGH0WMxxNpnpOOtVSEJzy43ntcCJ4ssDL7JlaT+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}