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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a2f401b4c93aaab6500a0f62cecf48fa309d4133768fa0e787950dfac70c09' 
  AND token = 'VI4krO0JOordUyol3giePtOEq4uMbshudikmla/5oB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}