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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b90a102ca2f2a07a916e00b1d01174c35251a0ba6befb1dcec3c56379de9e7' 
  AND token = 'HCPq2R+zwqO3sfCneW3jxD7YBbMFlHcth1TqIiBchrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}