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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a607595bf4d4e26d7a69f54dbb3ed61265771a26b04d65d22f013643fc6c7dad' 
  AND token = '6T3Tp5zMuhhJht3Tbyve+ggRDkk/dSVc4WeiDj4oDaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}