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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1cd0bf9788ca97e42ef0551f707b7c57729868a3df436659c615955ad5f6597' 
  AND token = 'cX0Ccm7f8ejFFZMjygyVLZu6UByJgXNaw+Sg1bsKzB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}