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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd4aa89adcb4713355d4efbe95f49fa84db420efc754db15f55f844f1894f5d' 
  AND token = '9652jDZ5xyMiHcifUw5FEt4CqoDRxmMjzj70mClSY/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}