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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65a46afda25a157f9a63c569c3df8c4b0afa8adb0d2e90f60446f63ac717086' 
  AND token = 'EBESBINoMsyZAPy+S5+R76BUsoLW0kgFoyxV3Qfztgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}