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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ba22bf9ace56f563c745f4edf04e9fcb9199157e2c24ab9d6b1c685c071b06' 
  AND token = 'KVg2BiAO3TjHs61jynAai2expztlzGfPKGEkDtOKlbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}