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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8e1ea93b372b1f01c4fb8d5637f801f99cb0e7b82a7baab1a5c25f097d4e5f' 
  AND token = 'uN1zukl2TR0b+cNc+jmP8yPe10jKtsdxyQVPUNL8NZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}