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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4bb3977c7a25ae197e93694bc6c7edc356d0d6486c58ec6359ace01cff03db' 
  AND token = 'MPPjKwBq4R5z8xWaMazDGMv86TrJ4KtwDLqTIy1uUwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}