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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1bb0ae45a2049869605d1271702b174250c76100a23c27d3833ae269fbe215' 
  AND token = 'vfGIInSVJ6S6+rp4jDDQMAHcspOaP6HViXQvaJhGrqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}