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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8e86da0becf6cbdba9932685ce79b7b5a36227fc958c6bbff1bfa3d398776d' 
  AND token = 'weeEpGtAO5npBcPRHf3Fc8AmAPywUHY1KcLjQtlEG4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}