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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1865cac867f567fb334c1507eae89d03b878131552ce9d33feb35f13998ed741' 
  AND token = '2M9wCd71//9ohyO8c68/zwWtTcN4QS2AIuCgap/A9vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}