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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b80162a26a27a5870e5284bf3b3fa13197de674dcf238632f565e9f1e6f693' 
  AND token = 'FOMIcGM+AgjscqpofdzIkdXAojEb9v1yfZY+snOqdGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}