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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04317755a2e5c46a7cab799af6278834b322a47977bbed19c5dcf7036df57489' 
  AND token = 'MeUAnHl4amrz6l2c10MXLE43oLNnatWn2BBbmJ/Oehc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}