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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3568580a2d68caa511fd58230a04c601c5df1ea2e0ec3bfc5439d1967e70e4' 
  AND token = 'LyAHKJWDHhzV+4l6PokHruIOIbe7tHHnkSP++/RhGwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}