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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f48bb7071354bdf3dfe0bc23075835d5e0f2b42e47a3936b6fe7337feb0e9ac' 
  AND token = 'RTFFvONLUuQhMxa3GuClbdLRljP+2IrH3i3hqLqWN5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}