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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3c197e9b67528fb4065aa5f26f2412188c6a9b5bd6d76abb8422c5f2ab1194' 
  AND token = 'Dp4mXyo0xcjMGDZqthENBjxmoS/oTNhgoZ84hSeaKTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}