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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10f7a315142b0c5e5c194111b612a9433f7bdaa1ace6c1b76d58079ae9b3962' 
  AND token = 'OX+Us/tob2SDvAKiJJIqOvDNuuVuSkZx52fnNKqdrzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}