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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1e866463d048150fe8b147c52e8a4fea281319437deca75a486f8f2a33b948' 
  AND token = 'qGjHnOsEZltSCHUPVKQELS45woEPYTSzaU3WGx0RscM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}