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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac86289abd014f71f2102d981cbd1a80aedf99fb9f0b5f3c727170d025fbfec0' 
  AND token = 'GZJE7SgT1jfKr4LUHR898CEdDn1C5fc9fLHeGCYzP/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}