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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7501b22aa366fc9b0d1d4bf02e2aa14b1900da8736603ddadce8d586daaba24' 
  AND token = 'GntcTn7JdVsOzswHa0EB5I1PzMBVEXa++HbG5hQ340Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}