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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1bf4c864d1b0611fdc0e85f24491ca0f756e2835adf74ab4685729763fc8d7' 
  AND token = 'SKZVkp6vlK906BCIiZFVlDr01bQTnL1AFFcd6vOuLA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}