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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cfc9cee5ef9663646008e68320b97d2aa58e13d400726515df74f5c2d7a825' 
  AND token = 'rt/bfBsWYEkfaPOCd37pgNf706qo53OnWhSvaPDYkts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}