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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe3d5ca585c3566c7a3ab80b62f06610d1c48f938dd9e514423ee808b43c557' 
  AND token = 'A43V7p5Ex4NjJ4Hj3Mvo/V/aP7fn6ic/dAhedEWzgy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}