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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a424edf3ec1c431ff6ed3a341ee4755738c11567466650a2926cf4a65bfe02' 
  AND token = '0Y7X69ee5XQI9bvYGEQg/6BbqLEfWXEKA9twzCu+gtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}