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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164544713fc6b45fa4f92e13c07ebd473b945a066538e4a8ea821f90d7b8b00f' 
  AND token = '6CmLCBCYXzkrnDbGkUAXXHSaR1YW5H+zYW99NMv4w4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}