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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c675f62edde64f3fb7eeb74a72324d5e9a1977b74ce79c3d705ad80758acf242' 
  AND token = 'JpDTQw5z96VGjc5p4bn8x7NWsCaFMvrexsc53SSHToY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}