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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66e010c385ca7704183231ced2028387b69b9f1c0439851e9e2a021e95d35db' 
  AND token = '6Z0iU1RfxSG8usiWX1VLj/ngyBuUAICc01A7xjc5yWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}