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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82fbfa7dedd22ccf8616d8f96afb0a4451d33c0e262c469cb4bdfff33ad2f564' 
  AND token = 'mPE2Hq9BpDzjytiK2PHKQOmC0xGbPtW2ZmYaMIz22B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}