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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349e775ab4288431ad95acad28bab7c1e9e95074436a7c82295748b99d8dfd88' 
  AND token = 'Aj/JRj2r+zwu6xAmfC9Yojtq7K3T+YjHe1/d/y7IW9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}