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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da43e11bd1e27328c927b9ce5b595a612d596984f2b73e8aa81e4f44cd1ac9e9' 
  AND token = 'th9JVRjjTJvEqujM+IGLNv7rThtuPHk8ILMmE18HaHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}