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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642caae536ced25d75bd3c78f29c009f20d590b4129e1c8dd9527ca956f4d557' 
  AND token = 'GehdX9MJqx4WEwC65N2rTV/cG+dTOG4Z56UJIEx5/s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}